Putting Tools in the Hands of Sites

The Research Resonance Network is a collaborative community of sites who are committed to the pursuit of excellence in clinical research operations. Tools available through the network assist sites with their continuous improvement, resource allocation, and study selection goals.

The Research Resonance Network is hosted by Forte Research Systems, Inc. as a service to the research community. Forte is dedicated to ensuring that sites have what they need to improve their own operations, and believes that site-based metrics are key to improving the clinical research industry as a whole. To create the most robust registry of site-based operational metrics available, participation is open to all sites pursuing excellence in clinical research operations through a data-driven approach, at no cost.

Forte Research Systems

A History of Data-Driven Operational Excellence

Forte Research Systems

Launched in early 2013, the network owes much of its success to the prior accomplishments of some of the nation’s top research centers. Initiatives around collecting and analyzing site-based operational performance metrics have been conducted since 2006 by a group known as Onsemble, which is comprised of organizations who use Forte’s OnCore® Enterprise Research system.

Timeline of Events

For years, it has been clear to the clinical research community that, in order to get the most benefit from performance metrics, the metrics must address the needs and operational workflows from the perspective of the sites.

Work began within the OnCore community in 2006. With the encouragement and support of Srini Kalluri, Founder, CEO and Chief Customer Officer at Forte, the initial projects were launched. These initiatives were spearheaded by Henry Durivage, PharmD, Associate Director for Regulatory Affairs and Clinical Research Systems at the Yale Center for Clinical Investigations and Kerry Bridges, MBA, RN, CCRC, Administrator at Indiana University Simon Cancer Center. Since then, the work has continued and more centers have participated, culminating in the Site Insights Dashboard now available through the Research Resonance Network.


In February, 2014, Research Resonance won the Clinical Informatics News Best Practices Award for Clinical Data Intelligence.



Metrics community begins as part of the Onsemble community collaborations.


Collaboration includes 8 participating organizations.

Metrics community focuses on Effort Tracking, Resource Management, and Protocol Performance.

Dr. Durivage & Kerry Bridges present a poster at ASCO Meeting "Clinical trial metrics: Protocol performance and resource utilization from 14 cancer centers". Download the poster.

Durivage HJ, Bridges KD: Clinical trial metrics: Protocol performance and resource utilization from 14 cancer centers. J Clin Oncol 27:337s, 2009 (suppl; abstr 6557).asco_2009


Onsemble Metrics collaborators establish initial Data Dictionary.

Dr. Durivage and Kerry Bridges present a poster at ASCO Meeting "Protocol Performance Metrics and Resource Utilization of Phase II Investigator-Initiated Trials". Download the poster.

Durivage HJ, Bridges KD, Sauers J, et al: Protocol performance metrics and resource utilization of phase II investigator-initiated trials. J Clin Oncol 28:463s, 2010 (suppl; abstr 6066)asco_2010


Jan: Forte joins MCC as a Corporate Sponsor and Collaborator — Forte actively participates in MCC calls defining Business and Clinical Metrics Objectives and Key Data Points.

Apr: Laura Youngquist, from Forte, authors, "Site-Driven Metrics," in March 2012 edition of Applied Clinical Trials.

Jun: Data Dictionary is released to Onsemble Metrics collaborators.

Aug: Article published in ACRP Monitor: "A Case for Site-Centric Operational Metrics," by Dr. Durivage & Srini Kalluri.

Durivage, HJ, Kalluri, S: A Case for Site-Centric Operational Metrics. The MONITOR. 26:4, 2012.


Jan: MCC Phase I is completed for both Business & Clinical workgroups completing the workflow mapping.

Feb: 20 participating organizations in the Onsemble Metrics collaboration.

Jul: Live data available in the Site Insights Dashboard on the Research Resonance Network.


Feb: Research Resonance Network wins Clinical Informatics News Best Practices Award for Clinical Data Intelligence.

Apr: Article published in the ACRP Clinical Researcher: The Need for a Standards-Based Approach to Staff Workload Tracking: A Case Study by Kerry Bridges, MBA, RN, CCRC; Linda Battiato, MSN, RN, OCN; J.T. Diener, CCRP; Inez Mattke, BS; Srini Kalluri, BS

Bridges, K, Battiatio, Linda, et. al: The Need for a Standards-Based Approach to Staff Workload Tracking: A Case Study. Clinical Researcher. April 2014.

May: A standard web services-based API becomes available. This means that any clinical trial management system (CTMS) can be connected to Research Resonance Network.


Feb: Network Insights Dashboard is launched for multi-site networks.

Mar: A new tradition begins with the Research Resonance Awards, a biannual recognition of the top performing member sites.

Jul: The Enrollment Progress Dashboard, a real-time view of protocols that are open to enrollment, is released.